The Duration of Postoperative Antibiotics in Autologous Breast Reconstruction: A Systematic Review and Meta-Analysis

Although prophylactic antibiotic use following autologous breast reconstruction post-mastectomy is a common practice, there no consensus in the literature regarding its duration. Antibiotic stewardship important to minimise multi-resistant organisms as well mitigate associated side effects. Currently, are published guidelines duration of antibiotics surgery mastectomy. The authors searched online administration for post-mastectomy. Preferred Reporting Items Systematic Reviews and Meta-Analysis were followed. primary outcome measure was incidence surgical site infections (SSIs). Three studies met inclusion criteria included total 1,400 patients. Overall, 101 (7.2%) SSIs observed. There significant difference rate when comparing less than or longer 24 hours postoperatively (odds ratio = 1.434, p 0.124). between with compared hours. Further form randomised controlled trials required assess effects